Why we all want the ‘Placental wellness complex’ by decima stem cells.
Placenta-derived slow-release therapy refers to using processed placenta (from human or animal sources) in a form that gradually releases its bioactive components (e.g., capsules or injections). This practice has been explored for potential health benefits in postpartum recovery and beyond. Below is a summary of research findings on how placenta-based therapy may support hormonal balance, energy levels, sleep, mood, stress resilience, and reproductive health. All information is drawn from peer-reviewed studies and presented in an FDA-compliant manner (i.e., avoiding unfounded claims).
Hormonal Balance
Natural Hormone Source
The placenta is a transient endocrine organ that produces a variety of hormones, including estradiol, progesterone, and human chorionic gonadotropin (hCG), which play key roles in regulating physiological functions. These hormones primarily affect the reproductive system and stress responses, which explains why placental components have been investigated for therapeutic effects on hormone-related conditions.
Menopausal Symptom Relief
A 12-week randomized placebo-controlled trial found that oral porcine placenta extract (300 mg/day) significantly improved menopausal symptom scores compared to placebo. Women taking the placenta supplement reported reductions in hot flashes, psychological symptoms, and somatic discomfort. Notably, estrogen (E2) and FSH levels did not change, suggesting symptom relief was achieved without directly altering hormone levels.
Postpartum Hormone Replenishment (Preliminary Data)
A pilot study found that mothers who took encapsulated placenta had small but significant increases in certain salivary hormone levels relative to placebo. However, these changes were modest and not enough to create significant overall hormonal differences, indicating that placenta capsules may offer subtle hormonal shifts rather than dramatic hormone restoration.
Energy and Chronic Fatigue
Traditional and Approved Uses
Placenta-based therapies have historically been used to combat fatigue and boost vitality. Injectable human placental extract (HPE) has been approved in Korea for improving fatigue and energy levels and has been widely used since 2003.
Chronic Fatigue Syndrome (CFS) – Injection Trial
A multicenter double-blind trial found that 6 weeks of subcutaneous human placenta extract injections led to significantly greater improvements in fatigue severity scores compared to placebo (p<0.05). No significant adverse effects were reported, indicating good tolerability.
Quality of Life and Stamina Improvements
A 5-week intravenous placenta extract study in CFS patients reported:
Significant reduction in chronic fatigue index scores
Notable gains in exercise capacity and stamina
Improvements in situational anxiety and depression
No reported safety issues
Sleep Optimization
Melatonin and Circadian Support
The placenta synthesizes melatonin, a hormone crucial for regulating sleep-wake cycles and circadian rhythms. Research confirms that placental cells actively produce melatonin and express melatonin receptors, suggesting that placenta-derived supplements may help support normal sleep patterns.
Indirect Benefits on Sleep-Related Symptoms
While direct evidence on placenta therapy improving sleep is limited, studies show improvements in menopausal symptoms and chronic fatigue, which often indirectly enhance sleep quality.
Mood and Stress Resilience
Postpartum Mood & Stress Reduction
A double-blind placebo-controlled study found no significant differences in mood or postpartum depression scores between placenta and placebo groups. However, separate research found that patients receiving placenta extract for chronic fatigue experienced significant drops in anxiety and depression scores.
General Mood and Stress Effects
Clinical trials indicate that placenta-derived bioactive factors may regulate the stress response, potentially improving resilience. Additional anti-fatigue and anti-inflammatory properties observed in studies suggest potential benefits for mood stabilization.
Libido and Reproductive Health
Hormones and Growth Factors for Fertility
Dried placenta is rich in estradiol, progesterone, testosterone, and small amounts of growth hormone, which are essential for reproductive function. Traditional Chinese Medicine has long used dried human placenta (Zi He Che) to enhance fertility and libido.
Sexual Function in Adults
A study in elderly Koreans (65+ years old) found that weekly placenta extract injections improved sexual satisfaction and overall quality of life.
Fertility and Sperm Health (Preclinical Data)
A controlled study of aging male rats found that placenta-fed rats had nearly double the sperm concentration of unsupplemented rats of the same age.
Conclusion
Placenta-derived slow-release therapies have attracted interest for a range of health applications. While clinical research supports benefits in menopause relief, chronic fatigue, and mood stabilization, other claims remain investigational.
These therapies should be approached as supportive treatments rather than guaranteed cures. Individuals interested in placenta therapy should consult healthcare professionals for guidance and ensure treatments adhere to proper safety and processing standards.
The Placental Wellness Complex by Decima embodies the latest in regenerative research, bringing these potential benefits to those seeking natural support for hormonal balance, energy, sleep, and overall vitality.
